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Natrium-Zirkonium-Cyclosilikat ist ein Ionenaustauscher zur Behandlung einer Hyperkaliämie. Es wird als Lokelma® unter dem Handelsnamen vertrieben und hat einen Zusatznutzen, der nicht belegt ist.

Lokelma is used for the treatment of hyper-kalaemia in adults. Hyperkalaemia means that the level of potassium in the blood is too high. Lokelma lowers the level of potassium in the body。

Lokelma 10 g administered three times daily lowered serum potassium by -0.7 mmol/L at 48 hours (p < 0.001 vs. placebo); statistically significant 14% potassium reduction was observed 1 hour after the first dose. Patients with higher starting。

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